Retinal Proteins: Photochemistry and Optogenetics
نویسندگان
چکیده
منابع مشابه
Interfacial photochemistry of retinal proteins
Retinal proteins are membrane-bound protein pigments that contain vitamin A aldehyde (retinal) as the chromophore. They include the visual pigment rhodopsin and four additional ones in the plasma membrane of Halobacterium salinarium (formerly Halobacterium halobium ). These proteins maintain a ®xed and asymmetric orientation in the membranes, and respond to a light stimulus by generating vector...
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Optogenetics is the use of genetic methods combined with optical technology to achieve gain or loss of function within neuronal circuits. The field of optogenetics has been rapidly expanding in efforts to restore visual function to blinding diseases such as retinitis pigmentosa (RP). Most work in the field includes a group of light-sensitive retinaldehyde-binding proteins known as opsins. Opsin...
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All-trans-Retinal (ATR) is a photosensitizer, serving as the chromophore for depolarizing and hyperpolarizing light-sensitive ion channels and pumps (opsins), recently employed as fast optical actuators. In mammalian optogenetic applications (in brain and heart), endogenous ATR availability is not considered a limiting factor, yet it is unclear how ATR modulation may affect the response to opti...
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excretory organs of fresh water organisms with the production of hypotonic urine by their excretory organs. From a more practical ecological view it is not clear to me that the authors have been critical in assessing whether states of acclimation, season of study, or source of animals were taken into account, in evaluating experimental evidence of others. On the positive side of the ledger the ...
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ژورنال
عنوان ژورنال: Bulletin of the Chemical Society of Japan
سال: 2020
ISSN: 0009-2673,1348-0634
DOI: 10.1246/bcsj.20190292